Mohs micrographic surgery in skin cancer

7 years’ ex-perience in uruguay

Authors

  • Sebastián Olivares Universidad de la República, Facultad de Medicina, Dermatología, Residente
  • Rodrigo Della Santa Dermatólogo
  • Alicia González Técnica en Anatomía Patológica
  • Verónica Lezué Técnica en Anatomía Patológica
  • Miguel Martínez Asuaga Universidad de la República, Facultad de Medicina, Dermatología, Profesor Titular. Dermatólogo
  • Carlos Bazzano Universidad de la República, Facultad de Medicina, Dermatología, Profesor Titular. Dermatólogo
  • Julio Magliano Universidad de la República, Facultad de Medicina, Dermatología, Profesor Adjunto. Dermatólogo, Cirujano de Mohs

DOI:

https://doi.org/10.29193/RMU.39.2.2

Keywords:

MOHS SURGERY, BASAL CELL CARCINOMA, SQUAMOUS CELL CARCINOMA

Abstract

Introduction: Mohs micrographic surgery is a technique for skin cancer exeresis involving the advantage of 100% of surgical margins histological exam, which leads to highest healing rates with the maximum preservation of the surrounding healthy tissue.
Objective: to conduct a clinical and epidemiological description of a 7 years’ experience in Uruguay.
Method: descriptive analysis of patients operated by the same Mohs surgeon who recorded clinical, tumor and surgical data.
Results: 641 surgeries were included in the study. 54.9% of surgeries were performed in men and 45.1% in women. Average age was 69 years old. 68.2% of cases corresponded to basal cell carcinoma and 31.8% to squamous cell carcinoma. 79.4% were located in the head and neck, 87.8% of tumors were primary and 11.1% were cases of relapse. The most frequent type of closure was simple in 48.7% of cases, followed by flaps in 31.7%.
Conclusions: Mohs surgery is a safe an effective procedure, and the results of the study agree with what is described in international reference centers. The study describes a 7 years’ experience in Uruguay of Mohs micrographic surgery, being it the largest research conducted in Uruguay.

References

Bittner GC, Cerci FB, Kubo EM, Tolkachjov SN. Mohs micrographic surgery: a review of indications, technique, outcomes, and consid-erations. An Bras Dermatol 2021; 96(3):263-77. doi: 10.1016/j.abd.2020.10.004.

Ríos-Buceta L, Picoto A. Cirugía de Mohs. Actas Dermosifiliogr 2003; 94(8):503-23.

Bichakjian CK, Olencki T, Aasi SZ, Alam M, Andersen JS, Berg D, et al. Basal cell skin cancer, version 1.2022, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw 2022; 14(5):574-97.

Wong E, Axibal E, Brown M. Mohs Micrographic Surgery. Facial Plast Surg Clin North Am 2019; 27(1):15-34. doi: 10.6004/jnccn.2016.0065.

Lee DA, Miller SJ. Nonmelanoma skin cancer. Facial Plast Surg Clin North Am 2009; 17(3):309-24. doi: 10.1016/j.fsc.2009.04.004.

Kallini JR, Hamed N, Khachemoune A. Squamous cell carcinoma of the skin: epidemiology, classification, management, and novel trends. Int J Dermatol 2015; 54(2):130-40. doi: 10.1111/ijd.12553.

Alonso T, Sánchez P, González A, Ingelmo J, Ruiz I, Delgado S, et al. Mohs micrographic surgery: our first 100 patients. Actas Dermosi-filiogr 2008; 99(4):275-80.

Macfarlane L, Waters A, Evans A, Affleck A, Fleming C. Seven years’ experience of Mohs micrographic surgery in a UK centre, and development of a UK minimum dataset and audit standards. Clin Exp Dermatol 2013; 38(3):262-9. doi: 10.1111/ced.12108.

Cortés-Peralta EC, Garza-Rodríguez V, Vázquez-Martínez OT, Gutié-rrez-Villarreal IM, Ocampo-Candiani J. Cirugía micrográfica de Mohs: 27 años de experiencia en el Noreste de México. Cir Cir 2017; 85(4):279-83. doi: 10.1016/j.circir.2016.10.022.

Ruiz-Salas V, Garcés JR, Miñano Medrano R, Alonso-Alonso T, Rodríguez-Prieto MÁ, López-Estebaranz JL, et al. Descripción de los pacientes intervenidos mediante cirugía de Mohs en España. Datos basales del registro español de cirugía de Mohs (REGESMOHS). Actas Dermosifiliogr 2015; 106(7):562-8.

Cardoso F DSB. Mohs micrographic surgery: a study of 83 cases. An Bras Dermatol 2011; 87(2):228-34. doi: 10.1590/s0365-05962012000200006.

Leibovitch I, Huilgol SC, Selva D, Richards S, Paver R. Basal cell carcinoma treated with Mohs surgery in Australia I. Experience over 10 years. J Am Acad Dermatol 2005; 53(3):445-51. doi: 10.1016/j.jaad.2005.04.083.

Brandão CM, Weimann ETS, Terzian LR, Machado Filho CDS, Paschoal FM, Criado PR. Keep it simple. A ten-year experience in reconstructions after Mohs micrographic surgery. An Bras Dermatol 2020; 95(6):714-20. doi: 10.1016/j.abd.2020.05.004.

Tan E, Mortimer N, Salmon P. Full-thickness skin grafts for surgical defects of the nasal ala: a comprehensive review, approach and outcomes of 186 cases over 9 years. Br J Dermatol 2014; 170(5):1106-13. doi: 10.1111/bjd.12792.

Magliano J, Navarrete J, Martínez M, Bazzano C. Cirugía micrográfica de Mohs en Uruguay: primeros 130 casos en carcinomas cutáneos. Rev Méd Urug 2018; 34(1):64-87. doi: 10.29193/rmu.34.1.3.

Published

2023-05-25

How to Cite

1.
Olivares S, Della Santa R, González A, Lezué V, Martínez Asuaga M, Bazzano C, et al. Mohs micrographic surgery in skin cancer: 7 years’ ex-perience in uruguay. Rev. Méd. Urug. [Internet]. 2023 May 25 [cited 2024 Nov. 21];39(2):e202. Available from: https://revista.rmu.org.uy/index.php/rmu/article/view/1025

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