Toxocariasis: clinical and laboratory manifestations in children assisted in a private comprehensive healthcare provider of Montevideo, Uruguay. 2014-2018
DOI:
https://doi.org/10.29193/RMU.36.1.1Keywords:
TOXOCARIASISAbstract
Introduction: human toxocariasis is a widely distributed parasitosis around the world. Its etiological agents are Toxocara canis and Toxocara cati in a smaller proportion.
Objective: to describe the clinical and paraclinical manifestations of toxocariasis in children younger than 15 years old who were assisted in a private comprehensive healthcare provider in Montevideo between 2014 and 2018.
Method: descriptive, retrospective study of children under 15 years old who were referred to the infectology service between January 1, 2014 and December 31, 2018 with a diagnosis of toxocariasis confirmed by ELISA. Variables were age, sex, reason of consultation, clinical manifestations, leukocyte and eosinophils count and associated parasitosis, treatment and evolution.
Results: 20 children were assisted, 11 of them were asymptomatic, 5 evidenced visceral larva migrans (VLM) syndrome and 4 of them presented larva migrans ocular (LMO). 20 patients received albendazon and one of them also received mebendazol. Those whose eyes were compromised also received oral corticoids. Two patients presented loss of visual acuity.
Discussion and conclusions: Most children were asymptomatic, 25% of them consulted for visual alterations whose sequelae represented a potentially preventable severe health problem. We need to make a greater effort to insist on eye control for children since alterations may be detected, avoiding sequelae with an early diagnosis and the right treatment.
References
(2) López M, Martín G, Chamorro M, Alonso M. Toxocariasis en niños de una región subtropical. Medicina (B. Aires) 2005; 65(3):226-30.
(3) Altcheh J, Nallar M, Conca M, Biancardi M, Freilij H. Toxocariasis: aspectos clínicos y de laboratorio en 54 pacientes. An Pediatr 2003; 58(5):425-31.
(4) Guarín Patarroyo C. Situación de la toxocariasis en algunos países de Latinoamérica: revisión sistemática. Bogotá: Universidad Nacional de Colombia, Facultad de Medicina, Instituto de Salud Pública, Departamento de Salud Pública, 2014. Disponible en: www.bdigital.unal.edu.co/44413/1/715569. 2014.pdf. (Consulta: 24 enero 2018).
(5) Vázquez Tsuji O, Martínez Barbarosa I, Tay Zavala J, Ruíz Hernández A, Pérez Torres A. Verduras de consumo como probable fuente de infección de toxocara sp. para el hombre. Bol Chil Parasitol 1997; 52(3):47-50.
(6) Vargas C, Torres P, Jercic M, Lobos M, Oyarce A, Miranda J, et al. frequency of anti- toxocara spp. antibodies in individuals attended by the centro de salud familiar and environmental contamination with toxocara canis eggs in dog feces, in the coastal niebla town, Chile. Rev Inst Med Trop Sao Paulo 2016; 58:62.
(7) Peña I, Vidal F, del Toro A, Hernández A, Zapata M. Zoonosis parasitarias causadas por perros y gatos, aspecto a considerar en Salud Pública de Cuba. Rev Electrón Vet 2017; 18(10):1-11. Disponible en: https://www.redalyc.org/articulo.oa?id= 63653470002. (Consulta: 14 diciembre 2018).
(8) Herskovic P. Larvas migrantes. En: Atias Neghme A, ed. Parasitología clínica. 3 ed. Santiago de Chile: Mediterráneo, 1991:314-8.
(9) Huapaya P, Espinoza Y, Roldán W, Jiménez S. Toxocariosis humana: ¿problema de salud pública? An Fac Med 2009; 70(4):283-90 Disponible en: http://www.scielo.org.pe/ pdf/afm/v70n4/a10v70n4.pdf. (Consulta: 14 diciembre 2018).
(10) Breña J, Hernández R, Hernández A, Castañeda R, Espinoza Y, Roldán W, et al. Toxocariosis humana en el Perú: aspectos epidemiológicos, clínicos y de laboratorio. Acta Med Per 2011; 28(4):228-36. Disponible en: http://www.scielo.org.pe/ pdf/amp/v28n4/a10.pdf. (Consulta: 21 diciembre 2018).
(11) Griffin D, Despommier D. Tissue Nematodes. En: Long S, Prober Ch, Fischer M, eds. Principles and practice of pediatric infectious diseases. 5 ed. Philadelphia: Elsevier, 2018:1381-8.
(12) Wiœniewska-Ligier M, WoŸniakowska-Gêsicka T, Sobolewska-Dryjañska J, Markiewicz-JóŸwiak A, Wieczorek M. Analysis of the course and treatment of toxocariasis in children-a long-term observation. Parasitol Res 2012; 110(6):2363-71.
(13) Assandri E, Skapino E, Da Rosa D, Alemán A, Acuña A. Anemia, estado nutricional y parasitosis intestinales en niños pertenecientes a hogares vulnerables de Montevideo. Arch Pediatr Urug 2018; 89(2):86-98.
(14) Cabrera F, Iturralde A, Lena A, Saavedra M, La Cámera M, García L, et al. Enteroparasitosis en niños de dos Centros de Atención a la Infancia y la Familia (CAIF) del barrio Casavalle, Montevideo. Arch Pediatr Urug 2017; 88(6):315-21.
(15) Vickery BP. Eosinófilos. En: Kliegman R, StantonB, St. Geme J, Schor N. Nelson tratado de pediatría. 20 ed. Philadelphia: Elsevier, 2016:1086-9.
(16) Yunus M, Tan Farrizam S, Abdul Karim I, Noordin R. A lateral flow rapid test for human toxocariasis developed using three toxocara canis recombinant antigens. Am J Trop Med Hyg 2018; 8(1):32-8.
(17) El-Sayed N, Ramadan M. Toxocariasis in children: an update on clinical manifestations, diagnosis, and treatment. J Pediatr Infect Dis 2017; 12(4):222-7.
(18) Hernández S, Contera M, Acuña A, Elhordoy D, Vignolo J. Toxocara spp en muestras de suelos y heces de plazas de la ciudad de Montevideo. Rev Patol Trop 2003; 32(1):95-104.
(19) Holcman Spector B, Olague G, Couto A. Helmintiasis del perro vagabundo (Canis familiaris) en la ciudad de Montevideo. Rev Urug Patol Clin 1985; 21:67-73.
(20) Correa O, Cabrera A. Estudio de relevamiento parasitario de caninos urbanos. En: Jornada de parasitología para estudiantes, I. Montevideo: UdelaR, Facultad de Veterinaria, nov.1998.
(21) Roldán W, Espinoza Y, Huapaya P, Jiménez S. Diagnóstico de la toxocariasis humana. Rev Perú Med Exp Salud Pública 2010; 27(4):613-20.
(22) Smith H, Holland C, Taylor M, Magnaval J, Schantz P, Maizels R. How common is human toxocariasis? Towards standardizing our knowledge. Trends Parasitol 2009; 25(4):182-8.