Trasplante heterotópico de corteza ovárica en paciente joven con cáncer de cuello uterino

Francisco Cóppola; Jorge Martínez; Álvaro Domínguez; Héctor Pérez Campos; Elías Regules; Fernanda Nozar; Sara Parada; Rafael Aguirre

Authors

Francisco Cóppola Universidad de la República, Facultad de Medicina, Clínica Ginecotocológica "C", Prof. Adj. Endocrinología., Ex asistente. Sociedad de Endocrinología Ginecológica del Uruguay, Presidente
Jorge Martínez Universidad de la República, Facultad de Medicina, Clínica Ginecotocológica "C", Prof. Agdo. Encargado de Ginecología de Clínica Ginecotocológica "C"
Álvaro Domínguez Universidad de la República, Facultad de Medicina, Clínica Ginecotocológica "C", Ex Asistente. Ginecólogo especialista en Reproducción Humana
Héctor Pérez Campos Uruguay. Ministerio de Salud Pública, Banco Nacional de Órganos y Tejidos, Área criopreservados, Médico coordinador
Elías Regules Universidad de la República, Facultad de Medicina, Departamento de Anatomía Normal, Prof. Agdo. Clínica Ginecotocológica "C", Ex Asistente
Fernanda Nozar Universidad de la República, Facultad de Medicina, Clínica Ginecotocológica "C", Residente
Sara Parada Centro Hospitalario Pereira Rossell, Unidad de Ecografía Ginecológica, Médico ecografista
Rafael Aguirre Universidad de la República, Facultad de Medicina, Clínica Ginecotocológica "C", Ex Asistente

Keywords:

NEOPLASMS OF THE UTERINE NECK, HETEROTOPIC TRANSPLANTATION

Abstract

Prognosis and cure rates of cervical cancer have increased during the last years due to early diagnosis and improved treatment. However, early diagnosis implies that a greater number of young women carriers of this disease are exposed to a iatrogenic affection of the wombs, as a consequence of cancer treatment. Preservation of ovarian endocrine function aims to prevent consequences of premature menopause and potential risks of hormonal replacement therapy. The purpose of this paper is to show the results of an auto-transplant of ovarian tissue to a heterotopic site (biceps).
A 33-year-old woman with a stage 1B cervical cancer underwent a surgery. One ovary was transferred to an extra-pelvic site and the other was auto-transplanted to the arm to prevent it from radiotherapy exposure. Post-surgical follow up showed a constant level of sexual steroids and fast revascularization of transplanted fragments at a biceps level. This procedure is seen as an adequate option to preserve endocrine function in young women with cervical cancer.

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