Diagnostic value of CT and Pet CT for detection of peritoneal carcinomatosis

Preliminary study

Authors

  • Álvaro Castro Universidad de la República, Facultad de Medicina, Hospital Pasteur, Clínica Quirúrgica “1”
  • Leandro Telles Universidad de la República, Facultad de Medicina, Hospital Pasteur, Clínica Quirúrgica “1”
  • Gabriela Rodríguez Cantera Universidad de la República, Facultad de Medicina, Hospital Pasteur, Clínica Quirúrgica “1”
  • Daniel González Universidad de la República, Facultad de Medicina, Hospital Pasteur, Clínica Quirúrgica “1”
  • Fernando González Universidad de la República, Facultad de Medicina, Hospital Pasteur, Clínica Quirúrgica “1”
  • Luis Ruso Martínez Universidad de la República, Facultad de Medicina, Hospital Pasteur, Clínica Quirúrgica “1”

DOI:

https://doi.org/10.29193/RMU.36.2.5

Keywords:

PERITONEAL NEOPLASMS, CARCINOMA, PERITONEUM, INDUCED HYPERTHERMIA, POSITRON-EMISSION TOMOGRAPHY, X-RAY COMPUTED TOMOGRAPHY

Abstract

Imagenology contributes to the accurate diagnosis of peritoneal compromise in the assessment of peritoneal carcinomatosis, although its effectiveness is still limited. CT is the most frequently used study and PET/CT is graduallly more requested in the assessment of different neoplasms. This study aims to assess performance of CT and PET/CT for diagnosis of peritoneal carcinomatosis in digestive and gynecological tumours.
Method: retrospective, observational study of 11 cases operated on peritoneal carcinomatosis after a CT and/or PET/CT had been performed. The results of both image studies were analysed separately and altogether and they were subsequently compared to intraoperative and pathology studies.
Results: CT matched findings in 8 out of 10 cases (sensitivity 78%, specificity 100%, positive predictive value 100%, negative predictive value 33%), whereas PET/TC matched in 9 out of 11 patients (sensitivity 100%, PPV 81%). When considered together, sensitivity was 100% y el PPV de 82%.
Conclusions: the results of the study confirm imagenology studies overestimate peritoneal carcinomatosis based on the characteristics of nodules and its uptake pattern. In CT/PET, SUV> 6 could increase the probability of diagnosing carcinomatosis. This small series of cases enables our suggesting CT and 18F-FDG PET-TC to be requested and analysed together to increase its efficiency, although surgical exploration continues to be the most effective method to diagnose and assess peritoneal carcinomatosis.

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Published

2020-04-21

How to Cite

1.
Castro Álvaro, Telles L, Rodríguez Cantera G, González D, González F, Ruso Martínez L. Diagnostic value of CT and Pet CT for detection of peritoneal carcinomatosis: Preliminary study. Rev. Méd. Urug. [Internet]. 2020 Apr. 21 [cited 2024 Nov. 21];36(2):155-62. Available from: https://revista.rmu.org.uy/index.php/rmu/article/view/531

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