Thyroid diseases and diabetes mellitus in patients during hip and knee replacement preoperative period

Authors

  • Cristina Goldner Universidad de la República, Facultad de Medicina, Clínica Médica. Profesora Agregada. Internista
  • María Soledad Velázquez Universidad de la República, Facultad de Medicina, Medicina Preventiva y Social. Ex Profesora Adjunta. Epidemióloga
  • Ana María Castiglioni Universidad de la República, Facultad de Medicina, Clínica Médica. Profesora Agregada. Internista
  • Mariella Barbi
  • Carolina Parodi
  • Antonio Blanco
  • Mónica Denniel
  • Laura Ramos
  • Marianela Maiche
  • Gonzalo Ruiz
  • José David Santos
  • María Piñeyrúa
  • Fernando Ramos Médico Evaluador de Grupo Asesor Médico. Internista

Keywords:

DIABETES MELLITUS, HYPOTHYROIDISM, HYPERTHYROIDISM, PREVALENCE, OBESITY, OVERWEIGHT

Abstract

Introduction: In spite of it being a rather frequent condition, not much is known about thyroid dysfunction in our country. The study considered clinical physicians would profit from learning about the frequency of diagnosed cases.
Diabetes mellitus is an endocrinopathy that was widely studied in our country. The figures corresponding to thyroid dysfunction and diabetes mellitus were compared in the sample studied.
Objective: to determine the frequency rate of thyroid dysfunction in a sample made up of patients evaluated in the second opinion preoperative period, candidates for a coordinated knee or hip replacement surgery, under coverage by the Fondo Nacional de Recursos (FNR)* and of diabetes mellitus, and to compare them to international frequencies.
Method: specific data on thyroid dysfunction and diabetes mellitus were obtained for patients referred to the Medical Consulting Group, who carried out a second opinion evaluation.
Results: 1.879 patients were included in the study, 67.2% of them being women, ranging from 22 to 101 years old, average age was 69.7±9.8 years old.
The study revealed that 17.6% evidenced thyroid dysfunction (95% confidence interval: 16.0%-19.5%); 22.6% in women and 7.5% in men. 97% of individuals with thyroid dysfunction had hypothyroidism.
Likewise, prevalence of diabetes mellitus was also studied, representing 13.5% of the sample (confidence interval 95%: 11.4% - 5.2%), 12.9% of them being women and 14.4% being men.
Conclusions: prevalence of thyroid dysfunction found in the sample was 17.6%, higher than that found for diabetes mellitus, which was 13.5%. The high frequency of overweight and obesity (83.4%) was a further finding of the study.

* National Fund to cover certain treatments.

References

(1) Klein I. Endocrine disorders and cardiovascular desease. En: Zipes DP, Libby P, Borrow R, Braunwald E, eds. Braunwald’s Heart Disease: a Text book of Cardiovascular Medicine. 7 ed. Philadelphia: Saunders, 2005:2051-65.
(2) Ladenson PW, Singer PA, Ain KB, Bagchi N, Bigos ST, Levy EG, et al. American Thyroid Association guidelines for detection of thyroid dysfunction. Arch Intern Med 2000; 160(11):1573-5. Disponible en: http://www.endo.org/ club/ata.pdf. Consulta: 6 de agosto 2014.
(3) Tunbridge WM, Evered DC, Hall R, Appleton D, Brewis M, Clark F, et al. The spectrum of thyroid disease in a community: the Whickham survey. Clin Endocrinol (Oxf) 1977; 7(6):481-93.
(4) Canaris GJ, Manowitz NR, Mayor G, Ridgway EC. The Colorado thyroid disease prevalence study. Arch Intern Med 2000; 160(4):526-34. Disponible En: http://www.collegepharmacy.com/images/download/Article_Forty_Percent_of_ Patients_Not_in_Normal_TSH_Range_Colorado_Study.pdf Consulta: 8 de junio 2014.
(5) Chile. Ministerio de Salud. Encuesta Nacional de Salud ENS Chile 2009-2010. Santiago: Ministerio de Salud, 2011. Disponible en: web.minsal.cl/portal/url/item/bcb 03d7bc28b64dfe040010165012d23.pdf. Consulta: 8 de junio 2014.
(6) Goldner C, López E, Serra P, Velázquez S, Collazo C, De León A, et al. Frecuencia de hipofunción tiroidea primaria en pacientes mayores de 60 años. En: Congreso Nacional de Medicina Interna, 36. Montevideo, 2007.
(7) López E, Yametti L, Serra P, Velázquez S, Collazo C, De León A, et al. Alteración de la función tiroidea en pacientes mayores de 60 años: importancia del laboratorio en su detección. En: Congreso Uruguayo de Bioquímica Clínica, 6. Montevideo, 2007.
(8) Federación Internacional de Diabetes. Atlas de la diabetes de la FID. 6 ed. Brussels: FID, 2014. Disponible en: http://www.idf.org/sites/default/files/Atlas-poster-2014_ES.pdf Consulta: 5 de enero 2015.
(9) Centers for Disease Control and Prevention. National Diabetes Fact Sheet: national estimates and general information on diabetes and prediabetes inthe United States, 2011. Atlanta, GA: CDC, 2011. Disponible en: http://www.cdc.gov/diabetes/pubs/pdf/ndfs_2011.pdf . Consulta: 2 de marzo 2014.
(10) Ferrero Petean R, García MV. Encuesta de prevalencia de la diabetes en el Uruguay: primera fase, Montevideo año 2004. Arch Med Interna (Montevideo) 2005; 27(1):7-12. Disponible en: http://www.intramed.net/contenidover.asp?contenidoID=36163&pagina=4. Consulta: 2 de marzo 2014.
(11) Organización Mundial de la Salud. 10 datos sobre la obesidad. Ginebra: OMS, 2014. Disponible en: http://www.who.int/features/factfiles/obesity/. Consulta: 8 de junio 2014.

Published

2015-09-30

How to Cite

1.
Goldner C, Velázquez MS, Castiglioni AM, Barbi M, Parodi C, Blanco A, et al. Thyroid diseases and diabetes mellitus in patients during hip and knee replacement preoperative period. Rev. Méd. Urug. [Internet]. 2015 Sep. 30 [cited 2024 Sep. 7];31(3):188-93. Available from: https://revista.rmu.org.uy/index.php/rmu/article/view/202

Most read articles by the same author(s)

1 2 > >>