Atrofodermia de Pasini-Pierini: Presentación de dos casos clínicos

Melina Farías; Santiago Boga; Gabriela Otero

doi:10.29193/RMU.38.4.9

Authors

Melina Farías Universidad de la República, Facultad de Medicina, Cátedra de Dermatología, Dermatología, Residente
Santiago Boga Universidad de la República, Facultad de Medicina, Cátedra de Dermatología, Dermatología, Posgrado de Dermatología
Gabriela Otero Universidad de la República, Facultad de Medicina, Cátedra de Dermatología Médico-Quirúrgica, Prof. Adjunta. Hospital Pereira Rossel, Centro Especializado en Tratamiento de Enfermedades de la Piel (CETEP), Dermatóloga

DOI:

https://doi.org/10.29193/RMU.38.4.9

Keywords:

BORRELIA BURGDORFERI, SCLERODERMA, ATROPHODERMA

Abstract

Atrophoderma of Pasini and Pierini is a rare disease, there being under 100 cases reported in literature. It is more frequent in women, and mainly occurs in their twenties or thirties. This condition results in dermal atrophy, and it may present as single or multiple plaques, with well-defined borders by differences in depth. The cause is unknown, although it has been related to Borrelia Burgdorferi infections. As to available therapies, there is no first line clinically proven treatment, although in some cases doxycycline is indicated for long periods.

The study presents two clinical cases of atrophoderma of Pasini and Pierini and reviews the main characteristics of this condition.

References

1) Maari C, Powell J. Atrofias del tejido conjuntivo. En: Bolognia JL, Schaffer JV, Cerroni L. Dermatologia. 4ª ed. Barcelona: Elsevier; 2019:1539-48.
2) Litaiem N, Idoudi S. Atrophoderma of Pasini and Pierini. Treasure Island, FL: StatPearls Publishing, 2022.
3) Buechner SA, Rufli T. Atrophoderma of Pasini and Pierini. Clinical and histopathologic findings and antibodies to Borrelia burgdorferi in thirty-four patients. J Am Acad Dermatol 1994; 30(3):441-6. doi: 10.1016/s0190-9622(94)70053-2.
4) Venzal JM, Nava S. El género Rickettsia como agente de zoonosis en el Cono Sur de Sudamérica. Rev Méd Urug 2011; 27(2):98-106. Dis-ponible en: https://revista.rmu.org.uy/index.php/rmu/article/view/396 [Consulta: 3 setiembre 2021].
5) Rapini RP. Alterations of conective tissue. En: Rapini RP. Practical Dermatopathology. 2nd. ed. Edinburgh: Elsevier, 2012:139-50.
6) Arpey CJ, Patel DS, Stone MS, Qiang-Shao J, Moore KC. Treatment of atrophoderma of Pasini and Pierini-associated hyperpigmentation with the Q-switched alexandrite laser: a clinical, histologic, and ultra-structural appraisal. Lasers Surg Med 2000; 27(3):206-12. doi: 10.1002/1096-9101(2000)27:3<206::aid-lsm2>3.0.co;2-1.