Síndrome de Lemierre: Caso y revisión de la literatura

Pedro Grille; Lucciano Grasiuso; Henry Albornoz

doi:10.29193/RMU.36.3.12

Authors

Pedro Grille ASSE, Hospital Maciel, UCI, Médico intensivista coordinador. Universidad de la República, Facultad de Medicina, Cátedra de Medicina Intensiva, Ex Prof. Adj.
Lucciano Grasiuso ASSE, Hospital Maciel, UCI, Médico residente de Medicina Intensiva
Henry Albornoz Universidad de la República, Facultad de Medicina, Cátedra de Enfermedades Infecciosas, Prof. Adj. ASSE, Hospital Maciel, UCI, Médico intensivista de guardia

DOI:

https://doi.org/10.29193/RMU.36.3.12

Keywords:

LEMIERRE SYNDROME, THROMBOPHLEBITIS, THROMBOEMBOLISM, PULMONARY EMBOLISM

Abstract

Lemierre’s syndrome constitutes a rare and potentially serious entity, that may complicate oropharyngeal infections. This condition includes thrombophlebitis of the internal jugular vein and distant septic embolisms. The study presents the clinical case of a young man who consulted after an upper respiratory infection, with internal jugular vein thrombosis, left sigmoid and transverse seins, also associating septic pulmonary embolism and pleural empyema. The patient had a positive evolution after empirical antibiotic, pleural drainage and anticoagulants.
We conducted literature review on this condition, focusing on clinical, epidemiological and microbiological aspects.

References

(1) Lemierre A. On certain septicaemia due to anaerobic organisms. Lancet 1936; 227(5874):701-3.
(2) Rivero Marcotegui M, Sánchez Rodríguez C, Cabal Soto S, Aizcorbe Garralda M. Síndrome de Lemierre y mycoplasma pneumoniae. An Med Interna (Madrid) 2005; 22(11):541-3.
(3) Johannesen KM, Bodtger U. Lemierre’s Syndrome: current perspectives on diagnosis and management. Infect Drug Resist 2016; 9:221-7.
(4) Riordan T, Kuppalli K, Livorsi D, Talati NJ, Osborn M. Lemierre’s Syndrome due to fusobacterium necrophorum. Lancet Infect Dis 2007; 20:622-59.
(5) Karkos PD, Asrani S, Karkos CD, Leong SC, Theochari EG, Alexopoulou TD, et al. Lemierre’s Syndrome: a systematic review. Laryngoscope 2009; 119(8):1552-9.
(6) Kuppalli K, Livorsi D, Talati NJ, Naasha J, Osborn M. Lemierre’s Syndrome due to fusobacterium necrophorum. Lancet Infect Dis 2012; 12(10):808-15.
(7) Kristensen LH, Prag J. Human necrobacillosis, with emphasis on Lemierre’s Syndrome. Clin Infect Dis 2000; 31(2):524-32.
(8) Riordan T. Human infection with fusobacterium necrophorum (Necrobacillosis), with a focus on Lemierre’s Syndrome. Clin Microbiol Rev 2007; 20(4):622-59.
(9) Tellería Martín A, Jiménez Urra I, Susperregui Insausti I, Ramos Castro J, Gutierrez Oliver YA. Sindrome de Lemierre. Med Intensiva 2005; 29(8):441-4.
(10) Montiel Crespo R, Quintero Otero S, Hernández González A, de Benito Guerra MT, García Trujillo I, Tinoco Rasero I, et al. Sindrome de Lemierre: la enfermedad olvidada. Med Intensiva 2005; 29(8):437-40.
(11) Alferijat M. A case of Lemierre’s Syndrome with a brief literature review. J Infect Public Health 2016; 9:681-3.
(12) Leoncini E, Ricciardi W, Cadoni G, Arzani D, Petrelli L, Paludetti G, et al. Adult height and head and neck cancer: a pooled analysis within the INHANCE Consortium. Head Neck 2014; 36(10):1391.
(13) Golpe R, Marín B, Alonso M. Lemierre ’s Syndrome (Necrobacillosis). Postgrad Med J 1999; 75(881):141-4.
(14) Eilbert W, Singla N. Lemierre ’s syndrome. Int J Emerg Med 2013; 6(1):40.
(15) Rebelo J, Nayan S, Choong K, Fulford M, Chan A, Sommer DD. To anticoagulate? Controversy in the management of thrombotic complications of head & neck infections. Int J Pediatr Otorhinolaryngol 2016; 88:129-35.
(16) De Smet K, Claus PE, Alliet G, Simpelaere A, Desmet G. Lemierre’s syndrome: a case study with a short review of literature. Acta Clin Belg 2019; 74(3):206-10.
(17) Cantero Macedo AM, Carrasco Seco MC, Forte Guerrero M, Bazo Fariñas AV, Callejo Calvo J. Lemierre’s syndrome, a serious complication of acute sinusitis. Actual Med 2016; 101(798):112-7.