Las fronteras entre el envejecimiento cognitivo normal y la enfermedad de Alzheimer

El concepto de deterioro cognitivo leve

Autores/as

  • Jorge Lorenzo Otero Universidad de la República, Facultad de Medicina, Hospital de Clínicas, Instituto de Neurología, Neuropsicología, Profesor Agregado. Médico Neurólogo
  • Luis Fontán Scheitler Universidad de la República, Facultad de Medicina, Hospital de Clínicas, Instituto de Neurología, Neuropsicología, Profesor Adjunto. Médico Neurólogo

Palabras clave:

ENFERMEDAD DE ALZHEIMER, TRASTORNOS COGNITIVOS

Resumen

Revisamos el concepto de envejecimiento cognitivo, la epidemiología de la enfermedad de Alzheimer (EA) y especialmente sus factores de riesgo y aquellos de protección que aseguran un envejecimiento exitoso. Concluimos que el anciano normal no tiene deterioro cognitivo significativo. Revisamos el concepto de deterioro cognitivo leve (DCL), sus fundamentos clínicos, la necesidad de su diagnóstico neuropsicológico, sus bases lesionales, sus marcadores imagenológicos y paraclínicos, discutiendo con mayor detalle la situación actual en lo referente a métodos imagenológicos. Insistimos en que el DCL es una entidad clínica de relevancia ya que en muchos pacientes es una etapa preclínica o precoz de EA. Sugerimos la existencia de distintos perfiles neuropsicológicos. Describimos la situación actual del tratamiento así como varias alternativas futuras. Seleccionamos algunas conclusiones generales de interés clínico.

Citas

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Publicado

2003-05-30

Cómo citar

1.
Lorenzo Otero J, Fontán Scheitler L. Las fronteras entre el envejecimiento cognitivo normal y la enfermedad de Alzheimer: El concepto de deterioro cognitivo leve. Rev. Méd. Urug. [Internet]. 30 de mayo de 2003 [citado 19 de mayo de 2024];19(1):4-13. Disponible en: https://revista.rmu.org.uy/index.php/rmu/article/view/951

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